Ultrasonography of CIMT and plaques as a surrogate as a surrogate atherosclerosis used for prediction of future stroke and peripheral cardiovascular diseases.

Abstract

The presented study proposed the sonographic evaluation of carotid intima media thickness (CIMT) and plaques correlated with age, gender and risk factors of hypertension and diabetes mellitus. The evaluation importance of CIMT and plaques are surrogate biomarkers for future cardiac disease, stroke and peripheral arteries disease. Patients and method: studied 84 patients (45 males and 39 females) which were referred to our hospital had vague complaint, hypertension, diabetes mellitus or referred patients had two risk factors of hypertension and diabetes mellitus. Ultrasound with high frequency transducer was used for carotid intima media thickness (CIMT) and plaques measurements for assessment of the atherosclerosis. Results: values of CIMT and plaques were increased gradually by increasing age as well as were higher in men than women and increased also in patients with risk factors, which are associated with cardiovascular disease or stroke. Conclusion: the asymptomatic and symptomatic patients were referred to the hospital for carotid ultrasound. CIMT and plaques predict future cardiovascular disease, stroke and peripheral artery disease (PAD). Ultrasound underwent for presented patients to determination and delineation of carotid arteries intima media thickness and plaques. CIMT and plaques were increased by age and higher in patients with risk factors, as well as higher in men than women.

References

1. Lee W. General principles of carotid Doppler ultrasonography, Ultrasonography 2014;33(1):11-17.
2. Gaarder M, Seierstad T. Measurements of carotid intima media thickness in non-invasive high-frequency ultrasound images: the effect of dynamic range setting, Cardiovascular ultrasound 2015;13:5 doi: 10.1186/1476-7120-13-5.
3. Matsuo H, Taniguchi N, Ozaki T, et al. Standard method for ultrasound evaluation of carotid artery lesions, J. Med. Ultrasonics 2009;36:501-518.
4. Onut R, Balanescu S, Constantinescu D, et al. Imaging atherosclerosis by carotid intima media thickness in vivo: How to, Where and in Whom ?, Maedica (Buchar) 2012;7(2):153-162.
5. Stein J.H, Wisconsin M. Carotid intima media thickness and vascular age: You are only as old as your arteries look, Journal of the American Society of Echocardiography 2004;17(6):686-689.
6. Lorenz M.W, von Kegler S, Steinmetz H, et al. Carotid intima media thickening indicates a higher vascular risk across a wide age range: Prospective data from the carotid atherosclerosis progression study (CAPS), Stroke 2006;37:87-92.
7. Stein J.H, Douglas P.S, Srinivasan S.R, et al. Distribution and cross sectional age related increases of carotid artery intima media thickness in young adults: The Bogalusa heart study, Stroke 2004;35:2782-2787.
8. de Groot E, van Leuven SI, Duivenvoorden R, et al. Measurement of carotid intima-media thickness to assess progression and regression of atherosclerosis. Nat Clin Pract Cardiovasc Med. 2008;5(5):280-8.
9. Simova I. Intima-media thickness: appropriate evaluation and proper measurement, described, E-Journal of Cardiology Practice 2015;13(21):pages from1/14 to 14/14.
10. Flu W-J, van Kuijk J-P, Hoeks S.E, et al. Intima media thickness of the common carotid artery in vascular surgery patients: A predictor of postoperative cardiovascular events, Am. Heart J. 2009; 158(2):202-208.
11. Gaitini D, Soudack M. Diagnosing carotid stenosis by doppler sonography, Journal of ultrasound in medicine (JUM) 2005;24(8):1127-1136.
12. Tresoldi S, Bigi R, Gregori D, et al. Comparison between carotid artery Doppler ultrasound and coronary calcium score as predictors of significant coronary artery disease in patients undergoing computed tomography coronary angiography, Cardiovascular Pharmacology; Open Access 2014;3(1):pages from 1/6 to 6/6 (PDF). DOI:10.4172/2329-6607.1000116.
13. Alpour M, Masri D, Mofazzali A, et al. Carotid artery intima media thickness in patients undergoing coronary artery bypass graft surgery. Archives of Cardiovascular Imaging 2013;1(1):26-30. DOI: 10.5812/acvi.12490. http://cardiovascimaging.com/12490.fulltext
14. Loizou C.P. A review of ultrasound common carotid artery image and video segmentation techniques, Medical & Biological Engineering & Computing 2014;52(12):1073-1093.
15. Bartels S, Franco A.R, Rundek T. Carotid intima media thickness (cIMT) and plaque from risk assessment and clinical use to genetic discoveries, Perspectives in Medicine 2012;1(12):139-145.
16. Jarauta E, Gallego R.M, Bea A, et al. Carotid intima media thickness in subjects with no cardiovascular risk factors, Rev Esp Cardiol. 2010;63(1):97-102.
17. Su T-C, Chien K-L, Jeng J-S, et al. Age and gender associated determinants of carotid intima media thickness: a community based study, Journal of atherosclerosis and thrombosis 2012;19(9):872-880.
18. Rashid S.A, Mahmud S.A. Correlation between carotid artery intima media thickness and luminal diameter with body mass index and other cardiovascular risk factors in adults, Sultan Qaboos University Med Journal 2015;15(3):344-350.
19. Juonala M, Kahonen M, Laitinen T, et al. Effect of age and sex on carotid intima-media thickness, elasticity and brachial endothelial function in healthy adults: The Cardiovascular Risk in Young Finns Study, European Heart Journal (2008) 29, 1198–1206 doi:10.1093/eurheartj/ehm556

Additional Files

Published

2018-10-14

How to Cite

Ultrasonography of CIMT and plaques as a surrogate as a surrogate atherosclerosis used for prediction of future stroke and peripheral cardiovascular diseases. (2018). Lebda Medical Journal, 5(1), 190–195. Retrieved from https://lebmedj.elmergib.edu.ly/index.php/LMJ/article/view/90